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In the field of molecular biology experiments, factors such as instrument space efficiency, operational throughput, and data reliability directly affect research progress and the quality of scientific outcomes. Addressing common laboratory challenges—limited deployment due to large instrument footprints, low efficiency in parallel sample processing, and insufficient data repeatability affecting result reliability—BigFisure’s newly launched FC-48D PCR Thermal Cycler adopts a dual-engine core architecture and intelligent system design to provide high-precision and high-efficiency PCR solutions for university research laboratories, biopharmaceutical R&D, and public health emergency testing.
The FC-48D achieves a significant breakthrough in spatial optimization with its compact body design. Without compromising performance, it dramatically reduces the footprint of the instrument, enabling flexible placement on standard laboratory benches, small R&D workstations, and even mobile testing vehicles where space is limited. This effectively resolves the long-standing issue of traditional PCR cyclers being “large and difficult to place.”
At the same time, the instrument features two independently controlled modules with a 48×2 sample capacity configuration, truly achieving “one machine, dual applications.” Users may run different protocols simultaneously (e.g., routine PCR amplification and primer specificity screening) or process multiple sample sets in parallel. This greatly enhances throughput per unit time, prevents research delays caused by limited instrument availability, and provides a solid hardware foundation for efficient high-volume experimentation.
Enhanced Temperature Control Performance & User Experience
Core Temperature Control Technology
At the heart of its performance, the FC-48D leverages BigFisure’s advanced thermoelectric semiconductor PID control technology to deliver exceptionally rapid heating and cooling rates. Compared with conventional PCR thermal cyclers, it shortens experiment duration by over 30%, easing time pressure for researchers working under tight project schedules.
More importantly, even at high-speed operation, the system maintains outstanding temperature accuracy and uniformity. At the critical reaction temperature of 55°C, the thermal block ensures consistent thermal conditions across all 96 wells of the dual-module system, minimizing temperature-induced variability and ensuring high repeatability and reliability of results.
To further support complex tasks such as primer optimization and reaction condition screening, the FC-48D includes a wide-range vertical temperature gradient capability. This allows researchers to evaluate multiple temperature parameters within a single run—eliminating repeated trial-and-error cycles and significantly reducing the operational burden of complex experiments.
Ease of Use & Experimental Safety
Balancing professional functionality with user-friendly design, the FC-48D includes:
- A 7-inch color touchscreen enabling intuitive program setup, parameter adjustment, and real-time monitoring
- Real-time graphical reaction status display for full visibility during the experiment
- Automatic pause and power-loss protection, safeguarding samples during power interruptions or program errors
- A smart heated lid that automatically adjusts to protect samples, maintain product stability, and support energy-efficient operation
Versatile Applications Across Research Fields
As a high-performance instrument designed for multi-domain use, the FC-48D supports a wide range of applications, including:
- Basic nucleic acid amplification
- High-fidelity amplification
- cDNA synthesis
- Library preparation
- And various other PCR-related workflows
It is engineered to meet the diverse and evolving needs of different scientific research projects.
If you would like to obtain a detailed technical datasheet, request a demo unit, or consult about purchasing, please contact our team using the phone number below.
Let the FC-48D become your accelerator for research efficiency!
Post time: Dec-11-2025
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